Control of Francisella tularensis Virulence at Gene Level: Network of Transcription Factors
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F20%3A00556422" target="_blank" >RIV/60162694:G44__/20:00556422 - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/2076-2607/8/10/1622" target="_blank" >https://www.mdpi.com/2076-2607/8/10/1622</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/microorganisms8101622" target="_blank" >10.3390/microorganisms8101622</a>
Alternative languages
Result language
angličtina
Original language name
Control of Francisella tularensis Virulence at Gene Level: Network of Transcription Factors
Original language description
Regulation of gene transcription is the initial step in the complex process that controls gene expression within bacteria. Transcriptional control involves the joint effort of RNA polymerases and numerous other regulatory factors. Whether global or local, positive or negative, regulators play an essential role in the bacterial cell. For instance, some regulators specifically modify the transcription of virulence genes, thereby being indispensable to pathogenic bacteria. Here, we provide a comprehensive overview of important transcription factors and DNA-binding proteins described for the virulent bacterium Francisella tularensis, the causative agent of tularemia. This is an unexplored research area, and the poorly described networks of transcription factors merit additional experimental studies to help elucidate the molecular mechanisms of pathogenesis in this bacterium, and how they contribute to disease.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Microorganisms
ISSN
2076-2607
e-ISSN
2076-2607
Volume of the periodical
8
Issue of the periodical within the volume
10
Country of publishing house
CH - SWITZERLAND
Number of pages
16
Pages from-to
1622
UT code for WoS article
000585373900001
EID of the result in the Scopus database
2-s2.0-85094601078