Analysis of Cumulative Fluid Balance Impact on the Stability of Gastrointestinal Tract Anastomosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F23%3A00558314" target="_blank" >RIV/60162694:G44__/23:00558314 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/22:10436768 RIV/00179906:_____/22:10436768

Result on the web

<a href="https://link.springer.com/article/10.1007/s12262-021-02831-0" target="_blank" >https://link.springer.com/article/10.1007/s12262-021-02831-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s12262-021-02831-0" target="_blank" >10.1007/s12262-021-02831-0</a>

Result language

angličtina

Original language name

Analysis of Cumulative Fluid Balance Impact on the Stability of Gastrointestinal Tract Anastomosis

Original language description

Anastomotic leakage is a serious postoperative complication following a low anterior resection of rectum. Current research in colorectal surgery focuses on searching for techniques which could minimize the risk of leakage. The main objective of this study was to evaluate the impact of cumulative fluid balance on microcirculatory changes at the anastomotic site.This experimental study used 15 domestic pigs; all of the animals underwent rectal resection. Then the animals were divided into three groups and received IV crystalloids at various rates, i.e. 5 ml/kg/h; 10 ml/kg/h; and 20 ml/kg/h. Large bowel micro-perfusion was measured using laser Doppler flowmetry during and following the surgical procedure.The experiments were successfully performed in all 15 cases. No animal died during the procedure or during the follow-up. We found no differences in micro-perfusion of the bowel between the experimental groups during the surgical procedure and during the follow-up period after the surgery. A significant decrease in micro-perfusion was observed after the transection of the inferior mesenteric artery in all the groups; again, no differences between the groups were observed.We did not confirm the original hypothesis that excessive load of IV crystalloids during the surgery would have a negative effect on bowel micro-perfusion and thus a negative effect on the healing of the anastomosis. However, laser Doppler flowmetry was found to have high accuracy in measuring tissue microcirculation and has the potential to be used in clinical practice.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30212 - Surgery

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Indian Journal of Surgery

ISSN

0972-2068

e-ISSN

0973-9793

Volume of the periodical

84

Issue of the periodical within the volume

1

Country of publishing house

IN - INDIA

Number of pages

5

Pages from-to

185-189

UT code for WoS article

000635066200001

EID of the result in the Scopus database

2-s2.0-85103667367