The effects of oregano oil on fungal infections associated with metabolic syndrome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG45__%2F20%3A00555806" target="_blank" >RIV/60162694:G45__/20:00555806 - isvavai.cz</a>

Result on the web

<a href="https://www.revistadechimie.ro/pdf/51%20GHITEA%20T%201%2020.pdf" target="_blank" >https://www.revistadechimie.ro/pdf/51%20GHITEA%20T%201%2020.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.37358/RC.20.1.7854" target="_blank" >10.37358/RC.20.1.7854</a>

Result language

angličtina

Original language name

The effects of oregano oil on fungal infections associated with metabolic syndrome

Original language description

This study aims to compare the evolution of mycosis associated with metabolic syndrome under allopathic treatment compared to phytotherapy using oregano essential oil. The study was conducted over a period of 6 months, on a total of 72 patients diagnosed with fungal infections associated with metabolic syndrome. The patients were divided into 3 groups, depending on the administered treatment: group 1: 24 patients who received allopathic treatment; group 2: 24 patients who received oregano oil treatment; group 3: control, which did not undergo any antifungal treatment. All three groups were subjected to specific diet therapy for mycosis. The patients were initially evaluated at 10 days after the begining of the treatment (to track mycotic disease evolution in the acute phase), at 60 days (to evaluate the recurrence of mycoses) and at 180 days to track recurrent disease. Most infections were acute (77.78%), the chronic ones representing only 5.56% of cases. There were also 12 cases with recurrent infections (16.67%), out of which 6 cases (8.33%) had previously shown resistance to Nystatin. In the 72 cases there was a sensitivity of 100.00% for oregano oil and Ketaconazolum, insignificantly higher than for Myconazolum (97.22%, p=0.157), but significantly higher than for Clotrimazolum and Nystatinum (94.44%, p=0.0437), Variconazole and Fluconazole (88.89%, p=0.0038) and Itraconazole (86.11%, p=0.0011). The results of this study showed an increased efficiency of oregano oil on the symptomatic and paraclinical improvement of mycotic infections in the study, both on short term and on long term, which was completed with high tolerability.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

50902 - Social sciences, interdisciplinary

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Revista de Chimie

ISSN

0034-7752

e-ISSN

—

Volume of the periodical

71

Issue of the periodical within the volume

1

Country of publishing house

RO - ROMANIA

Number of pages

7

Pages from-to

335-341

UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85079246491