Identification of Nitrogen Mustard Chemical Warfare Agents in Sand by Gas Chromatography–Mass Spectrometry (GC-MS) in a Military Deployable Laboratory

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG45__%2F24%3A00558041" target="_blank" >RIV/60162694:G45__/24:00558041 - isvavai.cz</a>

Result on the web

<a href="https://www.tandfonline.com/doi/abs/10.1080/00032719.2022.2081336" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/00032719.2022.2081336</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/00032719.2022.2081336" target="_blank" >10.1080/00032719.2022.2081336</a>

Result language

angličtina

Original language name

Identification of Nitrogen Mustard Chemical Warfare Agents in Sand by Gas Chromatography–Mass Spectrometry (GC-MS) in a Military Deployable Laboratory

Original language description

Nitrogen mustards are blistering chemical warfare agents which are considered to be persistent contaminants highly resistant to decontamination. The paper describes the development and optimization of a method for the extraction of nitrogen mustards bis(2-chloroethyl)ethylamine (HN-1), bis(2-chloroethyl)methylamine (HN-2), and tris(2-chloroethyl)amine (HN-3) from sand samples with subsequent identification by gas chromatography–mass spectrometry (GC-MS) in a military deployable laboratory. Common solvents which have been used for various methods in field analysis and are available in deployable laboratories were tested as the extraction reagents— dichloromethane, dichloroethane, hexane, heptane, ethyl acetate, methanol, and acetone. Calibration curves for the determination of nitrogen mustards were created. Methods for the extraction from the sand matrix were developed and optimized. The extraction efficiencies of the tested solvents were compared. Limits of detection of nitrogen mustards in sand samples were determined for all tested extractants. For quantitative purposes, the internal standardization method was used. The extraction efficiencies for the studied solvents varied in the range from 10.8 to 86.4%. The most effective extraction reagents for HN-1, HN-2, and HN-3 extraction were dichloromethane and acetone. Acetone was determined to be the most practical extraction reagent of nitrogen mustards in sand after the consideration of various criteria.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

ANALYTICAL LETTERS

ISSN

0003-2719

e-ISSN

1532-236X

Volume of the periodical

56

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

1-13

UT code for WoS article

000804602400001

EID of the result in the Scopus database

2-s2.0-85131382004