Eradication of Pinworm Infections from Laboratory Rat Colonies Using Ivermectin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F05%3A12618" target="_blank" >RIV/60460709:41210/05:12618 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Eradication of Pinworm Infections from Laboratory Rat Colonies Using Ivermectin

Original language description

Oxyurids (Syphacia muris and Aspiculuris tetraptera) are common contaminants of both conventional and specific pathogen-free rodent colonies. It is difficult to control because many anthelmintics eliminate adult worms but have no effect on ova, which cansurvive ex vivo for prolonged periods. The purpose of this study was to evaluate an efficiency of orally administered ivermectin diluted in water as treatment for pinworms in laboratory rat colonies. One hundred seventy rats naturally infected with pinworms (Syphacia muris and Aspiculuris tetraptera) were randomly divided into control and treated groups. The treated group of 120 rats was divided into ten subgroups of 12 animals each. Each subgroup received one to four courses of ivermectin which alternated with drinking water every 5 days. During each treatment, ivermectin was administered for 5 days in the drinking water; based on water consumption, the ivermectin dose was 2.5 mg/kg of body weight per day. Ova production was monitored

Czech name

Eradikace roupové infekce v chovu laboratorního potkana pomocí ivermektinu

Czech description

Oxyurids (Syphacia muris and Aspiculuris tetraptera) are common contaminants of both conventional and specific pathogen-free rodent colonies. It is difficult to control because many anthelmintics eliminate adult worms but have no effect on ova, which cansurvive ex vivo for prolonged periods. The purpose of this study was to evaluate an efficiency of orally administered ivermectin diluted in water as treatment for pinworms in laboratory rat colonies. One hundred seventy rats naturally infected with pinworms (Syphacia muris and Aspiculuris tetraptera) were randomly divided into control and treated groups. The treated group of 120 rats was divided into ten subgroups of 12 animals each. Each subgroup received one to four courses of ivermectin which alternated with drinking water every 5 days. During each treatment, ivermectin was administered for 5 days in the drinking water; based on water consumption, the ivermectin dose was 2.5 mg/kg of body weight per day. Ova production was monitored

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EG - Zoology

OECD FORD branch

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Project

<a href="/en/project/GD523%2F03%2FH076" target="_blank" >GD523/03/H076: Enhancing of Methodological Level and Theoretical Education of Students of the Ph. D. Program 4103V - Animal Husbandry - a Perspective Field General Animal Husb</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Helmintologia

ISSN

0440-6605

e-ISSN

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Volume of the periodical

42

Issue of the periodical within the volume

3

Country of publishing house

SK - SLOVAKIA

Number of pages

1

Pages from-to

1-1

UT code for WoS article

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EID of the result in the Scopus database

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