THE EVALUATION OF THE MELANOCORTIN-4 RECEPTOR OF THE RYANODINE-1 RECEPTOR AND THE INTERACTION BETWEEN THIS GENES ON CARCASS TRAIT IN PIGS

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F10%3A47723" target="_blank" >RIV/60460709:41210/10:47723 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

čeština

Original language name

The evalution of the melanocortin-4 receptor of the ryanodine-1 receptor and the interaction between this genes on carcass trait in pigs

Original language description

The melanocortin-4 receptor (MC4R) plays an important role in the control of mammalian energy homeostasis. In this context, many researches noted that a variant of the candidate gene MC4R may explain the significant variation in backfat thickness, growthrate, and feed intake in commercial pig hybrids. The aim of this study was demonstrated the effect mutation AF087937:c.746G>A in the MC4R gene, the effect causal mutation C1843T in the RYR1 gene and the interaction between these genes. In this study wasfound the significant influence of allele G in the MC4R gene and of allele n in the RYR1 gene on lean meat. Moreover, we did not find the interaction between these on killing out percentage. Also we assume, that allele G have influence on higher lean meat. In the contrary, we did not find an evidential influence of c.746G>A in the MC4R gene on fatness. We detected the significant influence only on backfat thickness and we did not find any trend of MC4R gene on fatness.

Czech name

The evalution of the melanocortin-4 receptor of the ryanodine-1 receptor and the interaction between this genes on carcass trait in pigs

Czech description

The melanocortin-4 receptor (MC4R) plays an important role in the control of mammalian energy homeostasis. In this context, many researches noted that a variant of the candidate gene MC4R may explain the significant variation in backfat thickness, growthrate, and feed intake in commercial pig hybrids. The aim of this study was demonstrated the effect mutation AF087937:c.746G>A in the MC4R gene, the effect causal mutation C1843T in the RYR1 gene and the interaction between these genes. In this study wasfound the significant influence of allele G in the MC4R gene and of allele n in the RYR1 gene on lean meat. Moreover, we did not find the interaction between these on killing out percentage. Also we assume, that allele G have influence on higher lean meat. In the contrary, we did not find an evidential influence of c.746G>A in the MC4R gene on fatness. We detected the significant influence only on backfat thickness and we did not find any trend of MC4R gene on fatness.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GG - Zootechnics

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Research in Pig Breeding - Výzkum v chovu prasat

ISSN

1802-7547

e-ISSN

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Volume of the periodical

4

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

5

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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