Fucosyllactose and L-fucose utilization of infant Bifidobacterium longum and Bifidobacterium kashiwanohense

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F16%3A71642" target="_blank" >RIV/60460709:41210/16:71642 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/s12866-016-0867-4" target="_blank" >http://dx.doi.org/10.1186/s12866-016-0867-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12866-016-0867-4" target="_blank" >10.1186/s12866-016-0867-4</a>

Result language

angličtina

Original language name

Fucosyllactose and L-fucose utilization of infant Bifidobacterium longum and Bifidobacterium kashiwanohense

Original language description

Background: Human milk oligosaccharides (HMOs) are one of the major glycan source of the infant gut microbiota. The two species that predominate the infant bifidobacteria community, Bifidobacterium longum subsp. infantis and Bifidobacterium bifidum, possess an arsenal of enzymes including alpha-fucosidases, sialidases, and beta-galactosidases to metabolise HMOs. Recently bifidobacteria were obtained from the stool of six month old Kenyan infants including species such as Bifidobacterium kashiwanohense, and Bifidobacterium pseudolongum that are not frequently isolated from infant stool. The aim of this study was to characterize HMOs utilization by these isolates. Strains were grown in presence of 2'-fucosyllactose (2'-FL), 3'-fucosyllactose (3'-FL), 3'-sialyl-lactose (3'-SL), 6'-sialyl-lactose (6'-SL), and Lacto-N-neotetraose (LNnT). We further investigated metabolites formed during L-fucose and fucosyllactose utilization, and aimed to identify genes and pathways involved through genome comparison.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BMC MICROBIOLOGY

ISSN

1471-2180

e-ISSN

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Volume of the periodical

16

Issue of the periodical within the volume

N

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

12

Pages from-to

1-12

UT code for WoS article

000386173300001

EID of the result in the Scopus database

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