Effects of Zearalenone, alpha Zearalenol, and Genistein on Boar Sperm Motility In Vitro
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F17%3A74031" target="_blank" >RIV/60460709:41210/17:74031 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.17221/19/2017-CJAS" target="_blank" >http://dx.doi.org/10.17221/19/2017-CJAS</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.17221/19/2017-CJAS" target="_blank" >10.17221/19/2017-CJAS</a>
Alternative languages
Result language
angličtina
Original language name
Effects of Zearalenone, alpha Zearalenol, and Genistein on Boar Sperm Motility In Vitro
Original language description
Genistein (GEN) and zearalenone (ZEA), environmental oestrogens commonly present in feedstuff for pigs, are known for their effects on reproductive functions. The aim was to verify the in vitro effects of 0,5 to 20 microM concentrations of GEN, ZEA and its metabolite alpha zearalenol (aZOL) on pig sperm motility. A dose dependent increase of the immotile sperm amount against fast and medium fast sperm clusters was observed with all three oestrogens from the lowest concentrations tested. Individual CASA (computer assisted sperm analysis) parameters of motile sperms seemed to be less sensitive indicators. This should be considered especially in toxicological research on a sperm model. Background of inconsistencies in to date published papers is discussed. The results shift the effective concentrations of ZEA, aZOL, and GEN to values achievable in vivo and raises the questions of risk assessment of these compounds in pig reproduction.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40201 - Animal and dairy science; (Animal biotechnology to be 4.4)
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Czech Journal of Animal Science
ISSN
1212-1819
e-ISSN
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Volume of the periodical
62
Issue of the periodical within the volume
10
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
11
Pages from-to
435-445
UT code for WoS article
000410144900004
EID of the result in the Scopus database
2-s2.0-85029177716