Influence of human milk oligosaccharides on adherence of bifidobacteria and clostridia to cell lines
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F17%3A75035" target="_blank" >RIV/60460709:41210/17:75035 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1556/030.64.2017.029" target="_blank" >http://dx.doi.org/10.1556/030.64.2017.029</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1556/030.64.2017.029" target="_blank" >10.1556/030.64.2017.029</a>
Alternative languages
Result language
angličtina
Original language name
Influence of human milk oligosaccharides on adherence of bifidobacteria and clostridia to cell lines
Original language description
Adhesion of gut bacteria to the intestinal epithelium is the first step in their colonization of the neonatal immature gut. Bacterial colonization of the infant gut is influenced by several factors, of which the most important are the mode of delivery and breast-feeding. Breast-fed infants ingest several grams of human milk oligosaccharides (HMOs) per day, which can become receptor decoys for intestinal bacteria. The most abundant intestinal bacteria in vaginally delivered infants are bifidobacteria, whereas infants born by cesarean section are colonized by clostridia. The influence of HMOs on the adhesion of five strains of intestinal bacteria (three bifidobacterial strains and two clostridial strains) to mucus-secreting and non-mucus-secreting human epithelial cells was investigated. Bifidobacterium bifidum 1 and Bifidobacterium longum displayed almost the same level of adhesion in the presence and absence of HMOs. By contrast, adhesion of Clostridium butyricum 1 and 2 decreased from 14,41% to 6,7
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA
ISSN
1217-8950
e-ISSN
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Volume of the periodical
64
Issue of the periodical within the volume
4
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
8
Pages from-to
415-422
UT code for WoS article
000418339500005
EID of the result in the Scopus database
2-s2.0-85038631483