Screening of model animals for experimental infection with equine cyathostomes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A73923" target="_blank" >RIV/60460709:41210/18:73923 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2478/sab-2018-03" target="_blank" >http://dx.doi.org/10.2478/sab-2018-03</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/sab-2018-03" target="_blank" >10.2478/sab-2018-03</a>

Result language
angličtina
Original language name
Screening of model animals for experimental infection with equine cyathostomes
Original language description
Various laboratory animals - mice (Mus musculus) of six strains, rabbits (Oryctolagus cuniculus), guinea pigs (Cavia porcellus), rats (Rattus norvegicus) and Mongolian gerbils (Meriones unguiculatus) were used for experimental infections with larvae of small strongyles (Cyathostominae), obtained from horse faeces and cultured to the infective larval stage L3. The attempt to transfer cyathostome larvae was aimed at developing a model for investigation of different aspects of the life cycle and biology of these nematodes in the laboratory. Some animals were immunized (hydrocortisone) for the duration of the study. The laboratory animals were orally infected with 2 - 10 thousands of sheathed or ex-sheathed L3 larvae of mixed cyathostome species. All attempts to inoculate any animal failed there was no larval development in the experimental rodents and it can be stated that none of the investigated animals may serve as a suitable model host for horse nematodes of the subfamily Cyathostominae.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30310 - Parasitology

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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