Metabolic transformation and urinary excretion of selenium (Se) in rats fed a Se-enriched defatted rapeseed (Brassica napus, L.) diet

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A77423" target="_blank" >RIV/60460709:41210/18:77423 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1039/c7mt00325k" target="_blank" >http://dx.doi.org/10.1039/c7mt00325k</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c7mt00325k" target="_blank" >10.1039/c7mt00325k</a>

Result language
angličtina
Original language name
Metabolic transformation and urinary excretion of selenium (Se) in rats fed a Se-enriched defatted rapeseed (Brassica napus, L.) diet
Original language description
Se-Enriched defatted rapeseed (Se-DRS), a by-product of rapeseed oil production, is high in Se. This study aimed to detect possible changes in Se-metabolism after Se-DRS consumption and to assess its suitability as a Se supplement in monogaster feed. In this experiment, rats were fed three types of diets differing in Se-form: soybean meal, Se-salt and Se-DRS. Potential differences in Se-metabolism were evaluated based on the total Se concentrations along with non-protein Se speciation patterns in the urine and blood serum of the rats. The total Se concentrations were determined using inductively coupled plasma-mass spectrometry (ICP-MS). Se compounds in the samples were identified through high-performance liquid chromatography/ICP-MS. The total Se excretion rate was dose-dependent, and excess of dietary Se was eliminated in the form of Se-sugar 1, regardless of the administered Se-form. The excretion dynamics of dietary selenomethionine (soybean meal) and methylselenocysteine (Se-DRS) were different
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10613 - Zoology

Project
<a href="/en/project/GA13-04580S" target="_blank" >GA13-04580S: Transformation and speciation of selenium in the food chain: the effect of selenium fortified diet</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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