The Roles of NO and H2S in Sperm Biology: Recent Advances and New Perspectives

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F20%3A81845" target="_blank" >RIV/60460709:41210/20:81845 - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/1422-0067/21/6/2174" target="_blank" >https://www.mdpi.com/1422-0067/21/6/2174</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms21062174" target="_blank" >10.3390/ijms21062174</a>

Result language
angličtina
Original language name
The Roles of NO and H2S in Sperm Biology: Recent Advances and New Perspectives
Original language description
After being historically considered as noxious agents, nitric oxide (NO) and hydrogen sulfide (H2S) are now listed as gasotransmitters, gaseous molecules that play a key role in a variety of cellular functions. Both NO and H2S are endogenously produced, enzymatically or non-enzymatically, and interact with each other in a range of cells and tissues. In spite of the great advances achieved in recent decades in other biological systems, knowledge about H2S function and interactions with NO in sperm biology is in its infancy. Here, we aim to provide an update on the importance of these molecules in the physiology of the male gamete. Special emphasis is given to the most recent advances in the metabolism, mechanisms of action, and effects (both physiological and pathophysiological) of these gasotransmitters. This manuscript also illustrates the physiological implications of NO and H2S observed in other cell types, which might be important for sperm function. The relevance of these gasotransmitters to sev
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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