Wastewater-based epidemiology to assess the occurrence of new psychoactive substances and alcohol consumption in Slovakia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F20%3AN0000111" target="_blank" >RIV/60460709:41210/20:N0000111 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S0147651320306011?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0147651320306011?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ecoenv.2020.110762" target="_blank" >10.1016/j.ecoenv.2020.110762</a>
Alternative languages
Result language
angličtina
Original language name
Wastewater-based epidemiology to assess the occurrence of new psychoactive substances and alcohol consumption in Slovakia
Original language description
Consumption of alcohol and new psychoactive substances (NPS) in a population or during special events (music festivals) is usually monitored through individual questionnaires, forensic and toxicological data, and drug seizures. However, consumption estimates have some biases due mostly to the unknown composition of drug pills for NPS and stockpiling for alcohol. The aim of this study was to evaluate for the first time the real use of alcohol and the occurrence of NPS in Slovakia by wastewater-based epidemiology (WBE). Urban wastewater samples were collected from nine Slovak cities over two years (2017-2018) and during three music festivals. The study included about 20% of the Slovak population and 50 000 festival attendees. The urinary alcohol biomarker ethyl sulfate (EtS) and thirty NPS were analyzed by liquid chromatography tandem mass spectrometry (LC MS MS). EtS concentrations were used for estimating the per capita alcohol consumption in each city. The average alcohol consumption in the selected cities and festivals in 2017 2018 ranged between 7 and 126 L day 1000 inhabitants and increased during the weekends and music festivals. Five NPS belonging to the classes of synthetic cathinones (mephedrone, methcathinone, buphedrone and pentedrone) and phenethylamines (25 iP NBoMe) were found in the low ng L range. Methcathinone was the most frequently detected NPS, while the highest normalized mass load corresponded to mephedrone (3,1 mg day 1000 inhabitants). Wastewater based epidemiology can provide timely information on alcohol consumption and NPS occurrence at the community level that is complementary to epidemiology based monitoring techniques (e.g. population surveys, police seizures, sales statistics).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30108 - Toxicology
Result continuities
Project
<a href="/en/project/EF16_019%2F0000845" target="_blank" >EF16_019/0000845: Centre for investigation of synthesis and transformation of nutritional substances in the food chain in interaction with potentially harmful substances of athropogenic origin: assessment of contamination risks for the quality of production</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Ecotoxicology and Environmental Safety
ISSN
1090-2414
e-ISSN
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Volume of the periodical
200
Issue of the periodical within the volume
September
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
1-8
UT code for WoS article
000539092800044
EID of the result in the Scopus database
2-s2.0-85085025137