CRISPR-Based Genome Editing Tools: Insights into Technological Breakthroughs and Future Challenges

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F21%3A88659" target="_blank" >RIV/60460709:41210/21:88659 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/2073-4425/12/6/797" target="_blank" >https://www.mdpi.com/2073-4425/12/6/797</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/genes12060797" target="_blank" >10.3390/genes12060797</a>

Result language

angličtina

Original language name

CRISPR-Based Genome Editing Tools: Insights into Technological Breakthroughs and Future Challenges

Original language description

Genomeediting GE is having a tremendous influence around the globe in the life science community. Among its versatile uses, the desired modifications of genes, and more importantly the transgene DNAfree approach to develop genetically modified organism GMO, are of special interest. The recent and rapid developments in genomeediting technology have given rise to hopes to achieve global food security in a sustainable manner. We here discuss recent developments in CRISPRbased genomeediting tools for crop improvement concerning adaptation, opportunities, and challenges. Some of the notable advances highlighted here include the development of transgene DNAfree genome plants, the availability of compatible nucleases, and the development of safe and effective CRISPR delivery vehicles for plant genome editing, multigene targeting and complex genome editing, base editing and prime editing to achieve more complex genetic engineering. Additionally, new avenues that facilitate finetuning plant gene regulation ha

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10603 - Genetics and heredity (medical genetics to be 3)

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Genes

ISSN

2073-4425

e-ISSN

2073-4425

Volume of the periodical

12

Issue of the periodical within the volume

6

Country of publishing house

CH - SWITZERLAND

Number of pages

31

Pages from-to

1-31

UT code for WoS article

000667498800001

EID of the result in the Scopus database

2-s2.0-85107429839