Chemical Composition and Antistaphylococcal Activity of Essential Oil of <i>Curcuma mangga</i> Rhizome from Indonesia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F24%3A100849" target="_blank" >RIV/60460709:41210/24:100849 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41340/24:100849

Result on the web

<a href="https://doi.org/10.3390/separations11020049" target="_blank" >https://doi.org/10.3390/separations11020049</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/separations11020049" target="_blank" >10.3390/separations11020049</a>

Result language

angličtina

Original language name

Chemical Composition and Antistaphylococcal Activity of Essential Oil of <i>Curcuma mangga</i> Rhizome from Indonesia

Original language description

This study assessed the antistaphylococcal activity of essential oil (EO) hydrodistilled from the rhizome of Curcuma mangga grown in Indonesia using the broth microdilution volatilization method and standard broth microdilution method modified for evaluation of volatile agents, as well as described its chemical composition using gas chromatography (GC) with mass spectrometry (MS). A fused-silica HP-5MS column and a DB-17MS column were used to separate the components into two columns. The results demonstrated that the EO exhibited antistaphylococcal activity at the minimum inhibitory concentration (MIC) ranging from 128 to 1024 mu g/mL. In contrast, the clinical isolate of tetracycline-resistant Staphylococcus aureus was the most sensitive strain (MIC 128 mu g/mL). The major constituents of the EO were 15,16-dinorlabda-8(17),11-dien-13-one (24.63/15.78%), followed by ambrial (16.12/10.97%), 13-nor-eremophil-1(10)-en-11-one (7.16/6.21%), 15,16-dinorlabda-8(17),12-dien-14-al (6.61/11.57%), and aromadendrene oxide (5.98/3.77%). These results propose C. mangga rhizome EO as a promising agent for developing natural-based anti-infective preparations.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10406 - Analytical chemistry

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Separations

ISSN

2297-8739

e-ISSN

2297-8739

Volume of the periodical

11

Issue of the periodical within the volume

2

Country of publishing house

CH - SWITZERLAND

Number of pages

13

Pages from-to

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UT code for WoS article

001173094000001

EID of the result in the Scopus database

2-s2.0-85185970531