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The Evolutionary Landscape of Human Genome Vocabulary

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41320%2F15%3AN0000043" target="_blank" >RIV/60460709:41320/15:N0000043 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The Evolutionary Landscape of Human Genome Vocabulary

  • Original language description

    An inspection of the full vocabulary of the words (16-mers) of the human genome reveals that the top of the list, ranked by word occurrence, contains almost exclusively simple repeats and words from Alu sequences - the most abundant dispersed elements. These excessive words can be considered generators and suggest a simple model of genome evolution: an everlasting intrusion of the generator sequences in the neutral regions of the genome and gradual mutational changes causing an increase in sequence complexity. The way to detect the generators is to find those words all mutated forms of which appear less frequently. Examples of the generators are presented.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů