In Vitro Enzyme Inhibitory Properties, Secondary Metabolite Profiles and Multivariate Analysis of Five Seaweeds
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41320%2F20%3A84340" target="_blank" >RIV/60460709:41320/20:84340 - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/1660-3397/18/4/198" target="_blank" >https://www.mdpi.com/1660-3397/18/4/198</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/md18040198" target="_blank" >10.3390/md18040198</a>
Alternative languages
Result language
angličtina
Original language name
In Vitro Enzyme Inhibitory Properties, Secondary Metabolite Profiles and Multivariate Analysis of Five Seaweeds
Original language description
Seaweeds have been exploited as both food products and therapeutics to manage human ailments for centuries. This study investigated the metabolite profile of five seaweeds (Halimeda spp., Spyridia hypnoides (Bory de Saint-Vincent) Papenfuss, Valoniopsis pachynema (G. Martens) Borgesen, Gracilaria fergusonii J. Agardh and Amphiroa anceps (Lamarck) Decaisne using ultra-high-performance liquid chromatography coupled with electrospray ionization mass spectrometry (UHPLC-ESI-MS/MS). Furthermore, these seaweeds were assessed for antioxidant and inhibitory effects against alpha-amylase, alpha-glucosidase, acetyl-cholinesterase (AChE), butyryl-cholinesterase (BChE) and tyrosinase. Valoniopsis pachynema and A. anceps yielded the highest flavonoid (4,30 +/- 0,29 mg RE/g) and phenolic content (7,83 +/- 0,08 mg RE/g), respectively. Additionally, A. anceps exhibited significant antioxidant properties with all assays and significantly depressed BChE (IC50 = 6,68 +/- 0,83 mg/mL) and alpha-amylase activities (IC50 =
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30107 - Medicinal chemistry
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Marine Drugs
ISSN
1660-3397
e-ISSN
—
Volume of the periodical
18
Issue of the periodical within the volume
4
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
16
Pages from-to
1-16
UT code for WoS article
000533909300043
EID of the result in the Scopus database
2-s2.0-85083204583