RNAi biopesticides for precision control of invasive pests and pathogens in 3D forests: Quantum leap towards eco-friendly alternatives
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41320%2F25%3A103555" target="_blank" >RIV/60460709:41320/25:103555 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2352186425003906?pes=vor&utm_source=clarivate&getft_integrator=clarivate" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2352186425003906?pes=vor&utm_source=clarivate&getft_integrator=clarivate</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.eti.2025.104404" target="_blank" >10.1016/j.eti.2025.104404</a>
Alternative languages
Result language
angličtina
Original language name
RNAi biopesticides for precision control of invasive pests and pathogens in 3D forests: Quantum leap towards eco-friendly alternatives
Original language description
Climate change has severely amplified the frequency and severity of forest pest and pathogen outbreaks, leading to a decline in forest health, productivity, and biodiversity. Conventional pest management strategies, including chemical pesticides and mechanical removal, have proven largely ineffective or environmentally detrimental. RNA interference (RNAi) technology, particularly with nanotechnology, offers a promising and eco-friendly alternative for precisely controlling invasive forest pests and pathogens. Current review pinpoints significant advances in species-specific dsRNA design and delivery systems, including nanoparticle-based formulations such as chitosan, carbon quantum dots, liposomes, peptides, and layered double hydroxides that enhance the environmental stability, cellular uptake, and RNAi efficiency against different pests and pathogens. Moreover, delivery methods such as spray-induced and host-induced gene silencing (SIGS and HIGS) are also discussed, emphasising their feasibility in complex 3D forest environments. Recent advancements in software tools for species-specific dsRNA design, which democratise RNAi technology, were also presented. Finally, we assess the short-term and longterm environmental and ecotoxicological risks of RNAi-nanocomplexes, using foliar sprays and trunk injections, while highlighting the necessity to address species-specific sensitivity and ecological challenges, which are crucial for the market implementation of RNAi-nanobiopesticides. These assessments aim to increase forest resilience against biotic stressors under climate change and contribute to formulating a more refined, harmonised global framework for risk assessment of dsRNA-based biopesticides during large-scale forest applications.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20801 - Environmental biotechnology
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ENVIRONMENTAL TECHNOLOGY & INNOVATION
ISSN
2352-1864
e-ISSN
2352-1864
Volume of the periodical
40
Issue of the periodical within the volume
2025
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
34
Pages from-to
1-34
UT code for WoS article
001545718200004
EID of the result in the Scopus database
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