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Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41330%2F21%3A87062" target="_blank" >RIV/60460709:41330/21:87062 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.3390/v13061014" target="_blank" >https://doi.org/10.3390/v13061014</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/v13061014" target="_blank" >10.3390/v13061014</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers

  • Original language description

    Human herpesviruses are known to induce a broad spectrum of diseases, ranging from common cold sores to cancer, and infections with some types of these viruses, known as human oncogenic herpesviruses (HOHVs), can cause cancer. Challenges with viral latency, recurrent infections, and drug resistance have generated the need for finding new drugs with the ability to overcome these barriers. Berberine (BBR), a naturally occurring alkaloid, is known for its multiple biological activities, including antiviral and anticancer effects. This paper comprehensively compiles all studies that have featured anti-HOHV properties of BBR along with promising preventive effects against the associated cancers. The mechanisms and pathways induced by BBR via targeting the herpesvirus life cycle and the pathogenesis of the linked malignancies are reviewed. Approaches to enhance the therapeutic efficacy of BBR and its use in clinical practice as an anti-herpesvirus drug are also discussed.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10607 - Virology

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Viruses-Basel

  • ISSN

    1999-4915

  • e-ISSN

    1999-4915

  • Volume of the periodical

    13

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    18

  • Pages from-to

    1-18

  • UT code for WoS article

    000666015000001

  • EID of the result in the Scopus database

    2-s2.0-85107413107