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Evaluation of in vitro growth-inhibitory effect of carvacrol and thymol combination against Staphylococcus aureus in liquid and vapour phase using new broth volatilization chequerboard method

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41340%2F18%3A78108" target="_blank" >RIV/60460709:41340/18:78108 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.fitote.2018.07.002" target="_blank" >http://dx.doi.org/10.1016/j.fitote.2018.07.002</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.fitote.2018.07.002" target="_blank" >10.1016/j.fitote.2018.07.002</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Evaluation of in vitro growth-inhibitory effect of carvacrol and thymol combination against Staphylococcus aureus in liquid and vapour phase using new broth volatilization chequerboard method

  • Original language description

    Carvacrol and thymol, both plant derived volatile compounds, have extensively been studied individually as well as in combination with other agents for their antimicrobial activity in liquid phase. However, in contrast to well established assays for testing of antimicrobial combinatory effects in liquid media, there are no standardized methods for evaluation of interactions between volatile compounds in vapour phase. The objective of this study was to verify new broth volatilization chequerboard method by testing the combination of carvacrol and thymol and to determine in vitro inhibitory effect of these compounds in liquid and vapour phase against twelve Staphylococcus aureus strains. The new method, based on combination of standard microdilution chequerboard and new broth volatilization tests allowing calculation of fractional inhibitory concentrations (FICs), was used. Combination of carvacrol and thymol produced the additive antimicrobial effect against all strains tested. In several cases, they

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    21101 - Food and beverages

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Fitoterapia

  • ISSN

    0367-326X

  • e-ISSN

    1873-6971

  • Volume of the periodical

    129

  • Issue of the periodical within the volume

    September 2018

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    6

  • Pages from-to

    185-190

  • UT code for WoS article

    000443663800028

  • EID of the result in the Scopus database

    2-s2.0-85049574852