Effect of drug active substance particles on wet granulation process

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F07%3A00018549" target="_blank" >RIV/60461373:22310/07:00018549 - isvavai.cz</a>
Alternative codes found
RIV/67985858:_____/07:00091284
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Effect of drug active substance particles on wet granulation process
Original language description
The effect of the size and shape of drug active substance particles on wet granulation was studied. Active substances delivered by two different producers and active substance sampled from upper and lower levels of a storage container were used in pilot-plant expts. There were marked differences in particle size and shape according to bulk and tapped densities, sieve, and microscopy analyses. Consequently, marked fluctuations in granulation period, impeller power consumption and granulated mixt. temp. increases were detected by the pilot-plant expts. with investigated active substances.
Czech name
Vliv částic účinné látky léčiva na proces vlhké granulace
Czech description
Práce se zabývá vlivem vlastností částic účinné látky léčiva na proces vlhké granulace. Hlavní pozornost je věnována vlivu sypné a setřesné hustoty a granulometrickým vlastnostem částic.

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CI - Industrial chemistry and chemical engineering
OECD FORD branch
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Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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