Surface Modification of Biodegradable Poly(L-Lactic Acid) by Argon Plasma: Fibroblasts and Keratinocytes in the Spotlight

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F14%3A43897503" target="_blank" >RIV/60461373:22310/14:43897503 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22330/14:43897503

Result on the web

<a href="http://onlinelibrary.wiley.com/doi/10.1002/ppap.201400021/abstract" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/ppap.201400021/abstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/ppap.201400021" target="_blank" >10.1002/ppap.201400021</a>

Result language

angličtina

Original language name

Surface Modification of Biodegradable Poly(L-Lactic Acid) by Argon Plasma: Fibroblasts and Keratinocytes in the Spotlight

Original language description

Poly(L-lactic acid) [PLLA] is a biodegradable polymer of growing importance for applications in tissue engineering. This work deals with PLLA tuned by Ar plasma treatment (3 W) with the aim to enhance its wettability and cytocompatibility. Changes in surface properties of PLLA caused by plasma treatment were studied in relation to adhesion, proliferation, and metabolic activity of mouse embryonic fibroblasts (NIH 3T3) and human keratinocytes (HaCaT) in vitro. Plasma treatment of PLLA significantly improved adhesion and proliferation of both cell lines when compared to pristine PLLA. Changes in expression of adhesion molecules, talin 1 and vinculin, were also examined. The amount of both proteins in cells cultivated on modified PLLA matrices was lower than in cells grown on pristine PLLA after 24 h of incubation.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

<a href="/en/project/GBP108%2F12%2FG108" target="_blank" >GBP108/12/G108: Preparation, modification and characterization of materials by radiation</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Plasma Processes and Polymers

ISSN

1612-8850

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

11

Country of publishing house

DE - GERMANY

Number of pages

11

Pages from-to

1057-1067

UT code for WoS article

000344550900007

EID of the result in the Scopus database

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