DEGRADATION PRODUCTS OF PHARMACEUTICAL SUBSTANCES IN THE ELECTRIC FIELD

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F14%3A43898269" target="_blank" >RIV/60461373:22310/14:43898269 - isvavai.cz</a>
Result on the web
<a href="http://www.icct.cz/proceedings/2014/Full_Papers_ICCT_2014.pdf" target="_blank" >http://www.icct.cz/proceedings/2014/Full_Papers_ICCT_2014.pdf</a>
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
DEGRADATION PRODUCTS OF PHARMACEUTICAL SUBSTANCES IN THE ELECTRIC FIELD
Original language description
Pharmaceutical powders are prone to electrostatic charging by interact particles with equipment surface and the surface of other particles. The electrostatic charge of pharmaceutical powder particles affects properties of a raw material and all powder handling procedures, as the generated charge affects character and purity of final dosage form. The effect of electrostatic charge on composition of charged pharmaceutical substances was studied. The experimental charging was performed on samples of selected pharmaceutical substances and the charge was simulated by placing the samples in an electric field. The tested substances are morphinan alkaloids and trospium chloride. The electric fields were generated in two ways - corona discharge (2-10 kV) and byvoltage (15 kV) applied to electrodes attached to a glass horizontal tube. The experimental parameters were chosen to determination relationship between degradation process and the size of applied voltage, the period of charging or the c
Czech name
—
Czech description
—

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Proceedings of the 2nd International Conference on Chemical Technology
ISBN
978-80-86238-64-7
ISSN
—
e-ISSN
—
Number of pages
5
Pages from-to
470-474
Publisher name
Ocean Design
Place of publication
Prague
Event location
Mikulov, Czech Republic
Event date
Apr 7, 2014
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
—

Similar results(10)