L-Pro2 skin permeation enhancer: Molecular backgrounds of its mode of action

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F14%3A43898308" target="_blank" >RIV/60461373:22310/14:43898308 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

L-Pro2 skin permeation enhancer: Molecular backgrounds of its mode of action

Original language description

L-Pro2, (S)-N-acetylproline dodecylester, is a newly synthesized highly active skin permeation enhancer described recently [1]. This study contributes to elucidation of the mechanism of action of L-Pro2 using membrane models mimicking composition of thereal stratum corneum (SC) lipid matrix. The effect of L-Pro2 on the miscibility, fluidity and phase behaviour of the SC lipids has been studied by X-ray diffraction, IR- spectroscopy, and differential scanning calorimetry.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

<a href="/en/project/GA13-23891S" target="_blank" >GA13-23891S: Lipid membrane models – a new tool for studying pathophysiology of skin diseases at a molecular level</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

PBP World Meeting

ISBN

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ISSN

0939-6411

e-ISSN

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Number of pages

2

Pages from-to

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Publisher name

Elsevier B.V.

Place of publication

Netherlands

Event location

Lisbon, Protugalso

Event date

Mar 31, 2014

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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