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EFFECT OF TRIS AND HEPES BUFFERS ON THE GLASS-CERAMIC SCAFFOLD

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F15%3A43901145" target="_blank" >RIV/60461373:22310/15:43901145 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22310/15:43901147

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    EFFECT OF TRIS AND HEPES BUFFERS ON THE GLASS-CERAMIC SCAFFOLD

  • Original language description

    An in vitro test is commonly used for a prediction of a biomaterial ability to produce mineral hydroxyapatite on its surface. Tested biomaterial is exposed into simulated body fluid (SBF) [1]. SBF (prepared according ISO 23317 standard) mimics an inorganic part of a blood plasma and TRIS buffer tris(hydroxymethyl)amino-methane) is used for the pH = 7.45 keeping. Recently, we found [2] that TRIS buffer reacts with tested glass-ceramic material. Additionally, TRIS forms a soluble complex compound with Ca2+ ions, and thus it influences the in vitro test of glass-ceramic material. The aim of this work was to find whether HEPES buffer (C8H18N2O4S) could be able to maintain the pH of the simulated body fluid during the in vitro test.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    JH - Ceramics, fire-proof materials and glass

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/TE01020390" target="_blank" >TE01020390: Centre of the development of advanced metallic biomaterials for medical implants</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů