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Biocompatibility of modified Ultra high molecular weight polyethylene

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F16%3A43902711" target="_blank" >RIV/60461373:22310/16:43902711 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22330/16:43902711

  • Result on the web

    <a href="http://dx.doi.org/10.1117/12.2237379" target="_blank" >http://dx.doi.org/10.1117/12.2237379</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1117/12.2237379" target="_blank" >10.1117/12.2237379</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Biocompatibility of modified Ultra high molecular weight polyethylene

  • Original language description

    Ultra-high-molecular-weight polyethylene (UHMWPE, PE) is a synthetic polymer used for biomedical applications because of its high impact resistance, ductility and stability in contact with physiological fluids. Therefore this material is being used in human orthopedic implants such as total joint replacements. Surface modification of this material relates to changes of its surface hydrophilicity, energy, microstructure, roughness, and morphology, all influencing its biological response. In our recent work, PE was treated by an Ar+ plasma discharge and then grafted with biologically active polyethylene glycol in order to enhance adhesion and proliferation of mouse fibroblast (L929). The surface properties of pristine PE and its grafted counterparts were studied by goniometry (surface wettability). Furthermore, Atomic Force Microscopy was used to determine the surface morphology and roughness. The biological response of the L929 cell lines seeded on untreated and plasma treated PE matrices was quantified in terms of the cell adhesion, density, and metabolic activity.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    JJ - Other materials

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP108%2F12%2FG108" target="_blank" >GBP108/12/G108: Preparation, modification and characterization of materials by radiation</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Proceedings of SPIE Volume 9930 BIOSENSING AND NANOMEDICINE IX

  • ISBN

    978-1-5106-0251-9

  • ISSN

  • e-ISSN

  • Number of pages

    7

  • Pages from-to

    "UNSP 99300Y"

  • Publisher name

    SPIE the International Society for Optical Engineering

  • Place of publication

    Bellingham, WA

  • Event location

    San Diego

  • Event date

    Aug 28, 2016

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000389681300022