Dearomatization Strategy for the Synthesis of Arylated 2H-Pyrroles and 2,3,5-Trisubstituted 1H-Pyrroles

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F17%3A43914950" target="_blank" >RIV/60461373:22310/17:43914950 - isvavai.cz</a>

Result on the web

<a href="https://pubs.acs.org/doi/10.1021/acs.orglett.7b02219" target="_blank" >https://pubs.acs.org/doi/10.1021/acs.orglett.7b02219</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.orglett.7b02219" target="_blank" >10.1021/acs.orglett.7b02219</a>

Result language

angličtina

Original language name

Dearomatization Strategy for the Synthesis of Arylated 2H-Pyrroles and 2,3,5-Trisubstituted 1H-Pyrroles

Original language description

The first high-yielding route to arylated 2H-pyrroles was developed. The methodology utilizes 2,5-disubstituted pyrroles that are metalated, and the aryl substituents are introduced by a palladium-catalyzed cross coupling reaction. The prepared pyrroles can be rearranged to 2,3,5-trisubstituted pyrroles under acidic conditions. Attempts to convert the 2,3,5-trisubstituted pyrroles to 2,3,4,5-tetrasubstituted pyrroles by the dearomatization rearrangement strategy were unsuccessful.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10401 - Organic chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Organic Letters

ISSN

1523-7060

e-ISSN

—

Volume of the periodical

19

Issue of the periodical within the volume

17

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

4608-4611

UT code for WoS article

000409566400050

EID of the result in the Scopus database

2-s2.0-85028758429