Cytotoxicity of layered metal phosphorus chalcogenides (MPXY) nanoflakes; FePS3, CoPS3, NiPS3

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F18%3A43915746" target="_blank" >RIV/60461373:22310/18:43915746 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2452262718300473" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2452262718300473</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.flatc.2018.11.003" target="_blank" >10.1016/j.flatc.2018.11.003</a>

Result language
angličtina
Original language name
Cytotoxicity of layered metal phosphorus chalcogenides (MPXY) nanoflakes; FePS3, CoPS3, NiPS3
Original language description
Metal phosphorus chalcogenides is a new class of 2D materials that have shown interesting semiconducting, electronic, anisotropic, magnetic, dielectric, structural and optical properties. Recently, NiPS3, FePS3 and CoPS3 in particular have been highlighted for promising potential in important energy applications such as electrocatalysts for water splitting and hydrogen storage. However, little is known about the toxicological hazards that they may pose on humans. Here, we investigated the cytotoxicity of NiPS3, FePS3 and CoPS3 on human lung carcinoma cells (A549) and normal human bronchial cells (BEAS-2B) to address this concern. Upon treatment of these cells with different MPXY materials, we determined the remaining cell viability using water soluble tetrazolium salt (WST-8) assay. We found that CoPS3 was most toxic followed by FePS3 with intermediate toxicity while NiPS3 showed the lowest toxicity among the three materials tested for both cell lines. When viewed with other layered materials, these MPXY samples present comparable toxicities with transition metal dichalcogenides and black phosphorus at low concentrations.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
10402 - Inorganic and nuclear chemistry

Project
<a href="/en/project/GA17-11456S" target="_blank" >GA17-11456S: Layered transition metal dichalcogenides nanostructures for electrocatalysis</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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