The fundamental comparison of Zn-2Mg and Mg-4Y-3RE alloys as a perspective biodegradable materials

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F19%3A43919095" target="_blank" >RIV/60461373:22310/19:43919095 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/19:10401977

Result on the web

<a href="https://www.mdpi.com/1996-1944/12/22/3745/htm" target="_blank" >https://www.mdpi.com/1996-1944/12/22/3745/htm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ma12223745" target="_blank" >10.3390/ma12223745</a>

Result language

angličtina

Original language name

The fundamental comparison of Zn-2Mg and Mg-4Y-3RE alloys as a perspective biodegradable materials

Original language description

Biodegradable materials are of interest for temporary medical implants like stents for restoring damaged blood vessels, plates, screws, nails for fixing fractured bones. In the present paper new biodegradable Zn-2Mg alloy prepared by conventional casting and hot extrusion was tested in in vitro and in vivo conditions. Structure characterization and mechanical properties in tension and compression have been evaluated. For in vivo tests, hemispherical implants were placed into a rat cranium. Visual observation of the living animals, an inspection of implant location and computed tomography CT imaging 12 weeks after implantation were performed. Extracted implants were studied using scanning electron microscopy (SEM) on perpendicular cuts through corrosion products. The behaviour of zinc alloy both in in vitro and in vivo conditions was compared with commercially used Mg-based alloy (Mg-4Y-3RE) prepared by conventional casting and hot extrusion. Both compressive and tensile yield strengths of Zn and Mg-based alloys were similar; however, the brittleness of Mg-4Y-3RE was lower. Zn and Mg-based implants have no adverse effects on the behaviour or physical condition of rats. Moreover, gas bubbles and the inflammatory reaction of the living tissue were not detected after the 12-week period. © 2019 by the authors.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

20501 - Materials engineering

Project

<a href="/en/project/GA18-06110S" target="_blank" >GA18-06110S: Biodegradable zinc based alloys with optimized corrosion, mechanical and biological properties</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Materials

ISSN

1996-1944

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

22

Country of publishing house

CH - SWITZERLAND

Number of pages

6

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85075785893