Plasma-Activated Polyvinyl Alcohol Foils for Cell Growth

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F20%3A43920914" target="_blank" >RIV/60461373:22310/20:43920914 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/20:00537924 RIV/61389005:_____/20:00537924
Result on the web
<a href="https://www.mdpi.com/2079-6412/10/11/1083" target="_blank" >https://www.mdpi.com/2079-6412/10/11/1083</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/coatings10111083" target="_blank" >10.3390/coatings10111083</a>

Result language
angličtina
Original language name
Plasma-Activated Polyvinyl Alcohol Foils for Cell Growth
Original language description
Hydrogels, and not only natural polysaccharide hydrogels, are substances capable of absorbing large amounts of water and physiological fluids. In this study, we set out to optimize the process for preparing polyvinyl alcohol (PVA) hydrogels. Subsequently, we doped PVA foils with cellulose powder, with poly(ethylene glycol) (PEG) or with gold nanoparticles in PEG colloid solutions (Au). The foils were then modified in a plasma discharge to improve their biocompatibility. The properties of PVA foils were studied by various analytical methods. The use of a suitable dopant can significantly affect the surface wettability, the roughness, the morphology and the mechanical properties of the material. Plasma treatment of PVA leads to ultraviolet light-induced crosslinking and decreasing water absorption. At the same time, this treatment significantly improves the cytocompatibility of the polymer, which is manifested by enhanced growth of human adipose-derived stem cells. This positive effect on the cell behavior was most pronounced on PVA foils doped with PEG or with Au. This modification of PVA therefore seems to be most suitable for the use of this polymer as a cell carrier for tissue engineering, wound healing and other regenerative applications.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20501 - Materials engineering

Project
<a href="/en/project/GA19-02482S" target="_blank" >GA19-02482S: Ion beam writing synthesis of novel microstructures in advanced polymers and nanocomposites</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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