Single Plasmon-Active Optical Fiber Probe for Instantaneous Chiral Detection
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F20%3A43921123" target="_blank" >RIV/60461373:22310/20:43921123 - isvavai.cz</a>
Alternative codes found
RIV/61389005:_____/20:00522242
Result on the web
<a href="https://pubs.acs.org/doi/10.1021/acssensors.9b01328" target="_blank" >https://pubs.acs.org/doi/10.1021/acssensors.9b01328</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acssensors.9b01328" target="_blank" >10.1021/acssensors.9b01328</a>
Alternative languages
Result language
angličtina
Original language name
Single Plasmon-Active Optical Fiber Probe for Instantaneous Chiral Detection
Original language description
The chiral recognition of organic compounds is of vital importance in the field of pharmacology and medicine. Unfortunately, the common analytical routes used in this field are significantly restricted by time spent and equipment demands. In this work, we propose an unprecedented alternative, aimed at enantiomer discrimination and estimation of their concentrations in an uncomplicated and instantaneous manner. The proposed approach is based on the creation of an optical fiber probe with two pronounced plasmonic bands attributed to gold and silver. The gold or silver surfaces were grafted with moieties, able to enunciating entrap chiral amines from solution, resulting in a wavelength shift corresponding to each plasmonic metal. As a model compound of chiral amine, we chose the DOPA, also taking in mind its high medical relevancy. For chiral detection, the optical fiber probe was simply immersed in an analytical solution of DOPA, and the selective shift of gold or silver plasmon bands was observed in the reflected light depending on DOPA chirality. The observed shifts depend on the concentration of DOPA enantiomers. In the case of a racemic mixture, the shifts of both plasmonic bands emerge, making possible the simultaneous determination of enantiomer concentrations and their ratio. The analytical cycle takes several minutes and requires very simple laboratory equipment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20501 - Materials engineering
Result continuities
Project
<a href="/en/project/GA18-26170S" target="_blank" >GA18-26170S: Light triggerable p-conjugated polymers for ON/OFF reversible conductivity switching</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Sensors
ISSN
2379-3694
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
50-56
UT code for WoS article
000510079300009
EID of the result in the Scopus database
2-s2.0-85077471937