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Electrochemically oxidized 15-crown-5 substituted thiophene and host-guest interaction with new psychoactive substances

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F21%3A43921601" target="_blank" >RIV/60461373:22310/21:43921601 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22330/21:43921601 RIV/60461373:22340/21:43921601 RIV/60461373:22810/21:43921601

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0013468621001523?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0013468621001523?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.electacta.2021.137862" target="_blank" >10.1016/j.electacta.2021.137862</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Electrochemically oxidized 15-crown-5 substituted thiophene and host-guest interaction with new psychoactive substances

  • Original language description

    The aim of this work is to develop an impedimetric sensor using the principle of host- guest interaction for the detection of new psychoactive substances (NPSs). Synthesized 4 -( N -3- thiophenecarboxamido)benzo-15-crown-5 (TH3CA4AB15C5) was electrochemically deposited on the sur- face of a platinum disc electrode using cyclic voltammetry. Spectroscopic (infrared and NMR spec- troscopy) and electrochemical impedance spectroscopy (EIS) studies were applied to confirm the struc- ture of the polymeric film deposited onto the electrode surface and to evaluate its affinity towards 2- aminoindane (AI), 2-(methylamino)-1-phenylbutan-1-one (buphedrone, MABP) and 3 ,4 -methylenedioxy- α-pyrrolidinopropiophenone (MDPPP). These studies showed that the ease of formation hydrogen bonds between the product of electrochemical oxidation (TH3CA4AB15C5) and the above-mentioned analytes is the dominant factor for obtaining a useful analytical signal. The changes in the resistance to charge trans- fer obtained during the EIS measurements allowed: i ) to separately measure both the synthetic cathi- nones (MABP, MDPPP) and AI in the concentration range 1.99 x 10 –5 –1.22 x 10 –3 M; ii ) to quantify AI at levels of (1.6 –3.0) x 10 –4 M in the presence of various representatives from the NPS family.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Electrochimica Acta

  • ISSN

    0013-4686

  • e-ISSN

  • Volume of the periodical

    373

  • Issue of the periodical within the volume

    20 March 2021

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    137862

  • UT code for WoS article

    000621259000009

  • EID of the result in the Scopus database

    2-s2.0-85100674172