Effect of surface chemistry on bio-conjugation and bio-recognition abilities of 2D germanene materials

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F21%3A43922095" target="_blank" >RIV/60461373:22310/21:43922095 - isvavai.cz</a>

Result on the web

<a href="https://pubs.rsc.org/en/content/articlehtml/2021/nr/d0nr07579e" target="_blank" >https://pubs.rsc.org/en/content/articlehtml/2021/nr/d0nr07579e</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d0nr07579e" target="_blank" >10.1039/d0nr07579e</a>

Result language

angličtina

Original language name

Effect of surface chemistry on bio-conjugation and bio-recognition abilities of 2D germanene materials

Original language description

The interest of the scientific community for 2D graphene analogues has been recently focused on 2D-Xene materials from Group 14. Among them, germanene and its derivatives have shown great potential because of their large bandgap and easily tuneable electronic and optical properties. With the latter having been already explored, the use of chemically modified germanenes for optical bio-recognition is yet to be investigated. Herein, we have synthesized two germanene materials with different surface ligands namely hydrogenated germanene (Ge-H) and methylated germanene (Ge-Me) and used them as an optical platform for the label-free biorecognition of Ochratoxin A (OTA), a highly carcinogenic food contaminant. It was discovered that firstly the surface ligands on chemically modified germanenes have strong influence on the intrinsic fluorescence of the material; secondly they also highly affect both the bio-conjugation ability and the bio-recognition efficiency of the material towards the detection of the analyte. An improved calibration sensitivity, together with superior reproducibility and linearity of response, was obtained with a methylated germanene (Ge-Me) material, indicating also the better suitability of the latter for real sample analysis. Such research is highly beneficial for the development and optimization of 2D material based optical platforms for fast and cost-effective bioassays.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10402 - Inorganic and nuclear chemistry

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nanoscale

ISSN

2040-3364

e-ISSN

—

Volume of the periodical

13

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

1893-1903

UT code for WoS article

000612999200043

EID of the result in the Scopus database

2-s2.0-85100275972