Enzyme-Photocatalyst Tandem Microrobot Powered by Urea for Escherichia coli Biofilm Eradication
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F22%3A43924074" target="_blank" >RIV/60461373:22310/22:43924074 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/22:43924074 RIV/00216305:26620/22:PU145188 RIV/00216275:25310/22:39919093
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202106612" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202106612</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/smll.202106612" target="_blank" >10.1002/smll.202106612</a>
Alternative languages
Result language
angličtina
Original language name
Enzyme-Photocatalyst Tandem Microrobot Powered by Urea for Escherichia coli Biofilm Eradication
Original language description
Urinary-based infections affect millions of people worldwide. Such bacterial infections are mainly caused by Escherichia coli (E. coli) biofilm formation in the bladder and/or urinary catheters. Herein, the authors present a hybrid enzyme/photocatalytic microrobot, based on urease-immobilized TiO2/CdS nanotube bundles, that can swim in urea as a biocompatible fuel and respond to visible light. Upon illumination for 2 h, these microrobots are able to remove almost 90% of bacterial biofilm, due to the generation of reactive radicals, while bare TiO2/CdS photocatalysts (non-motile) or urease-coated microrobots in the dark do not show any toxic effect. These results indicate a synergistic effect between the self-propulsion provided by the enzyme and the photocatalytic activity induced under light stimuli. This work provides a photo-biocatalytic approach for the design of efficient light-driven microrobots with promising applications in microbiology and biomedicine.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Small
ISSN
1613-6810
e-ISSN
1613-6829
Volume of the periodical
18
Issue of the periodical within the volume
36
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
nestrankovano
UT code for WoS article
000751367200001
EID of the result in the Scopus database
2-s2.0-85124454727