3D-Printed SARS-CoV-2 RNA Genosensing Microfluidic System
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F22%3A43924075" target="_blank" >RIV/60461373:22310/22:43924075 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22350/22:43924075 RIV/00216305:26620/22:PU145148
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/admt.202101121" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/admt.202101121</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/admt.202101121" target="_blank" >10.1002/admt.202101121</a>
Alternative languages
Result language
angličtina
Original language name
3D-Printed SARS-CoV-2 RNA Genosensing Microfluidic System
Original language description
Additive manufacturing technology, referred as 3D printing technology, is a growing research field with broad applications from nanosensors fabrication to 3D printing of buildings. Nowadays, the world is dealing with a pandemic and requires the use of simple sensing systems. Here, the strengths of fast screening by a lab-on-a-chip device through electrochemical detection using 3D printing technology for SARS-CoV-2 sensing are combined. This system comprises a PDMS microfluidic channel integrated with an electrochemical cell fully 3D-printed by a 3D printing pen (3D-PP). The 3D-PP genosensor is modified with an ssDNA probe that targeted the N gene sequence of SARS-CoV-2. The sensing mechanism relies on the electro-oxidation of adenines present in ssDNA when in contact with SARS-CoV-2 RNA. The hybridization between ssDNA and target RNA takes a place and ssDNA is desorbed from the genosensor surface, causing a decrease of the sensor signal. The developed SARS-CoV-2/3D-PP genosensor shows high sensitivity and fast response.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Advanced Materials Technologies
ISSN
2365-709X
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
6
Pages from-to
nestrankovano
UT code for WoS article
000755350700001
EID of the result in the Scopus database
2-s2.0-85124624278