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pH Sensing for Early Detection of Septic Inflammation Based on Intrinsic Titanium β-Alloy Nanotubular Oxides

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F24%3A43929262" target="_blank" >RIV/60461373:22310/24:43929262 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.mdpi.com/2075-4701/14/2/229" target="_blank" >https://www.mdpi.com/2075-4701/14/2/229</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/met14020229" target="_blank" >10.3390/met14020229</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    pH Sensing for Early Detection of Septic Inflammation Based on Intrinsic Titanium β-Alloy Nanotubular Oxides

  • Original language description

    Orthopaedic surgeries like total hip and knee arthroplasty play a crucial role in restoring joint function for individuals with osteoarthritis. Deep bacterial infections are one of the most serious complications for orthopaedic implants. An infectious complication of an orthopaedic implant requires long-term and demanding treatment, often with repeated surgical procedures, and can lead to serious consequences such as implant failure, sepsis, and even death. Early detection of complications is of key importance for efficient therapy. The objective of this work is to investigate the possibilities of the nanotubular TiNbTa oxide for pH change sensing. Different surface treatments which lead to different surface natures were tested. For experiments, the inflammation was simulated by pH changes in the physiological solution. The response of the surface was monitored via the electrode potential changes. The results show that the nanotubular surface prepared on the TiNbTa alloy is a good possible candidate for pH sensing devices.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20501 - Materials engineering

Result continuities

  • Project

    <a href="/en/project/NU20-06-00424" target="_blank" >NU20-06-00424: Implantable sensors for early detection of infection and bacterial colonization</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Metals

  • ISSN

    2075-4701

  • e-ISSN

    2075-4701

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    12

  • Pages from-to

  • UT code for WoS article

    001168484300001

  • EID of the result in the Scopus database

    2-s2.0-85185659036