Synergistic removal of pharmaceuticals and antibiotic resistance from ultrafiltered WWTP effluent: free-floating ARGs exceptionally susceptible to degradation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22320%2F23%3A43925947" target="_blank" >RIV/60461373:22320/23:43925947 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0301479723006497?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0301479723006497?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jenvman.2023.117861" target="_blank" >10.1016/j.jenvman.2023.117861</a>
Alternative languages
Result language
angličtina
Original language name
Synergistic removal of pharmaceuticals and antibiotic resistance from ultrafiltered WWTP effluent: free-floating ARGs exceptionally susceptible to degradation
Original language description
To protect the environment and human health, antibiotic resistance genes (ARGs) and persistent pharmaceuticals need to be removed from WWTP effluent prior to its reuse. However, an efficient process for removing free-floating extracellular DNA (exDNA) in combination with a wide range of pharmaceuticals is yet to be reported for real process conditions. As a possible solution, we treated real ultrafiltered WWTP effluent with UV/H2O2 and combined GAC and zeolite sorption. In terms of exDNA, sequencing and high-throughput quantitative PCR (HT qPCR) showed that exDNA is a potent carrier of numerous ARGs in ultrafiltered WWTP effluent (123 ARGs), including multi-drug efflux pump mexF that became the dominant exARG in GAC effluent over time. Due to the exposure to degradation agents, exDNA was reduced more efficiently than intracellular DNA, and overall levels of ARGs were substantially lowered. Moreover, GAC sorption was particularly effective in the removal of almost all the 85 detected pharmaceutical residues, with fresh GAC demonstrating an efficiency of up to 100%. However, zeolite (Si/Al 0.8) addition was needed to enhance the removal of persistent pollutants such as gabapentin and diclofenac to 57% and up to 100%, respectively. Our combined approach eminently decreases the hazardous effects of pharmaceuticals and antibiotic resistance in the ultrafiltered WWTP effluent, producing effluent suitable for multiple reuse options according to the latest legislation. In addition, we provided similarly promising but less extensive data for surface water and treated greywater.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10503 - Water resources
Result continuities
Project
<a href="/en/project/TJ02000139" target="_blank" >TJ02000139: Development of technology eliminating micropollutants and antibiotic resistance genes input into the environment and the human organism</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Environmental Management
ISSN
0301-4797
e-ISSN
1095-8630
Volume of the periodical
340
Issue of the periodical within the volume
August 2023
Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
117861
UT code for WoS article
000989171900001
EID of the result in the Scopus database
2-s2.0-85153341490