Secreted aspartic proteases of Candida albicans, Candida tropicalis, Candida parapsilosis, Candida lusitaniae: inhibition with peptidomimetic inhibitors.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F01%3A00004481" target="_blank" >RIV/60461373:22330/01:00004481 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22330/01:00006079

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Secreted aspartic proteases of Candida albicans, Candida tropicalis, Candida parapsilosis, Candida lusitaniae: inhibition with peptidomimetic inhibitors.

Original language description

The secretion of aspartic proteases by Candida spp. was demonstrated to be one of the virulence determinants. Candida albicans is classified in the genus Candida as the major human pathogen. However, other species of this genus cause a candidiases. We designed and prepared an inhibitor containing phenylstatine isoster that was equipotent towards all four proteases within the range of 10-10 - 10-9 M. The HIV-1 protease inhibitors were also tested for the inhibition of four Saps.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/LN00A079" target="_blank" >LN00A079: Center of Integrated Genomics</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Europian Journal of Biochemistry

ISSN

0014-2956

e-ISSN

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Volume of the periodical

Neuveden

Issue of the periodical within the volume

268

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

2669-2677

UT code for WoS article

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EID of the result in the Scopus database

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