Pentosidine as a marker of human age in forensic medicine age estimation - přednes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F03%3A00008997" target="_blank" >RIV/60461373:22330/03:00008997 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Pentosidine as a marker of human age in forensic medicine age estimation - přednes
Original language description
Age estimation is a frequently asked question mainly in the cases of the autopsy of unidentified dead bodies. The forensic medicine has quite large menu of methods for age estimation which can be divided into morphologic and chemical. The analysis of a teeth, where morphologic methods (appreciation of attrition, root transparency, periodontal recession etc.) as well as chemical (analysis for D- aspartic acid) procedures can be applied, is considered to be the most reliable method for age estimation. A problem may arise when e.g. a dismembered dead body is found and no teeth are present. In such case, it should be useful to perform chemical analysis of soft tissues for markers of age. Unfortunately, until now there is no reliable method for age estimation from soft tissue. The analysis of posttranslational protein modification seems to be the possible way. One of these modifications is the formation of so called Advanced Glycation End products (AGE#s) in soft tissues. The pentosidin is
Czech name
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Czech description
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Project
<a href="/en/project/NK7281" target="_blank" >NK7281: Study of posttranslational modifications of human tissue proteins in relation to age</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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