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Lateral resolution in NALDI MSI: back to the future

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F15%3A43897788" target="_blank" >RIV/60461373:22330/15:43897788 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388971:_____/15:00444876 RIV/61989592:15310/15:33156419

  • Result on the web

    <a href="http://link.springer.com/article/10.1007%2Fs00216-014-8294-6" target="_blank" >http://link.springer.com/article/10.1007%2Fs00216-014-8294-6</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00216-014-8294-6" target="_blank" >10.1007/s00216-014-8294-6</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Lateral resolution in NALDI MSI: back to the future

  • Original language description

    Nanostructure-assisted laser desorption/ionization (NALDI) has been recognized as a powerful matrix-free mass spectrometry tool ideal for imaging of small molecules. In this report, the NALDI approach was compared with matrix-assisted laser desorption/ionization (MALDI) mass spectrometry in terms of sensitivity, reproducibility, and lateral resolution, which can be achieved in mass spectrometry imaging (MSI) experiments using a Nd:YAG laser. Scanning electron microscopy was used for surface topology analysis and evaluation of a putative surface-enhanced sensitivity effect, which was observed upon reduction of the laser focus. NALDI was identified as a more reproducible technique lacking MSI artifacts arising from distant tissue removal known from MALDI oversampling.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP206%2F12%2F1150" target="_blank" >GAP206/12/1150: Sampling and efficiency of atmospheric pressure desorption/ionization in mass spectrometric experiment</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytical and Bioanalytical Chemistry

  • ISSN

    1618-2642

  • e-ISSN

  • Volume of the periodical

    407

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    7

  • Pages from-to

    2141-2147

  • UT code for WoS article

  • EID of the result in the Scopus database