Carboxylic Carbon Quantum Dots as a Fluorescent Sensing Platform for DNA Detection
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F16%3A43901908" target="_blank" >RIV/60461373:22330/16:43901908 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/16:43901908
Result on the web
<a href="http://pubs.acs.org/doi/abs/10.1021/acsami.5b10160" target="_blank" >http://pubs.acs.org/doi/abs/10.1021/acsami.5b10160</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsami.5b10160" target="_blank" >10.1021/acsami.5b10160</a>
Alternative languages
Result language
angličtina
Original language name
Carboxylic Carbon Quantum Dots as a Fluorescent Sensing Platform for DNA Detection
Original language description
The demand for simple, sensitive, affordable, and selective DNA biosensors is ubiquitous, due to the important role that DNA detection performs in the areas of disease diagnostics, environment monitoring, and food safety. A novel application of carboxylic carbon quantum dots (cCQD) is highlighted in this study. Herein, cCQD function as a nanoquencher in the detection of nucleic acid based on a homogeneous fluorescent assay. To that purpose, the performance of two types of cCQD, namely, citric acid QD and malic acid QD, is evaluated. The principle behind the sensing of nucleic acid lies in the different propensity of single stranded DNA and double -stranded DNA to adsorb onto the surface of cCQD. For both types of cCQD, a superior range of detection of at least 3 orders of magnitude is achieved, and the potential to distinguish single-base mismatch is also exhibited. These findings are anticipated to provide valuable insights on the employment of cCQD for the fabrication of future DNA biosensors.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CA - Inorganic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA15-09001S" target="_blank" >GA15-09001S: Chemical modifications of graphene based materials: Synthesis of graphane and halogengraphene</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Applied Materials and Interfaces
ISSN
1944-8244
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
1951-1957
UT code for WoS article
000369044100049
EID of the result in the Scopus database
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