Peak bordering for ultrafast single particle analysis using ICP-MS

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F19%3A43917837" target="_blank" >RIV/60461373:22330/19:43917837 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22340/19:43917837

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0039914019300323?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0039914019300323?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.talanta.2019.01.030" target="_blank" >10.1016/j.talanta.2019.01.030</a>

Result language

angličtina

Original language name

Peak bordering for ultrafast single particle analysis using ICP-MS

Original language description

The characterisation of inorganic nanoparticles (NPs) by single particle inductively coupled plasma mass spectroscopy is possible only if the spectrometer is capable of measurement with high time-signal resolution. The latest generation of spectrometers allow for measurements with dwell times (dt) shorter than the 100 mu s gold standard, i.e. as low as 10 mu s. The statistical behaviours of signals obtained with dt values of 10, 20, 50, and 100 mu s were tested for 40, 60, and 100 nm silver NPs. Very low measured signals (units of counts) led to the occurrence of zero signal values inside the peaks corresponding to individual NPs. The probability of the occurrence of a zero signal inside the peak increased with decreasing dt and decreasing NP size. The standard approach to the bordering of the beginning and end of the peak by one zero signal point failed here and lead to the false detection of a larger number of smaller peaks. For example, in the case of 40 nm NPs a quadruple number of peaks were detected for a dt value of 10 mu s compared to the 100 mu s dt value; the mean peak width at 10 mu s dt was approximately 220 mu s, while at 100 mu s dt it was 550 mu s. The results tended to be less distorted when dt was longer and the NP size was larger. Low dt values also led to a distortion of the peak area distribution. For 40 nm NPs and 10 mu s, the most frequent peak area and the width of the peak area distribution were not evaluated due to a non-Gaussian course; 20 mu s dt caused (compared to 100 mu s) a decrease in the most frequent peak area by approximately 35% (33 counts for 100 mu s dt vs. 22 counts for 20 mu s dt) and an increase in the width of the peak area distribution by 70% (10 counts for 100 mu s dt vs. 17 counts for 20 mu s dt). Therefore, new approaches to bordering peaks were tested, which consisted of searching for an uninterrupted zero signal point sequence with a total length of 50 mu s or 100 mu s. Only the criterion of a 100 mu s delay between the two adjacent peaks resulted in values of the number of detected peaks, the most frequent peak areas, and the width of peak area distribution virtually independent of dt.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

<a href="/en/project/GA17-00291S" target="_blank" >GA17-00291S: Characterisation of inorganic nanoparticles by ultra-fast inductively coupled plasma mass spectrometry</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Talanta

ISSN

0039-9140

e-ISSN

—

Volume of the periodical

197

Issue of the periodical within the volume

MAY 15 2019

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

10

Pages from-to

189-198

UT code for WoS article

000460710200025

EID of the result in the Scopus database

2-s2.0-85059812327