Combination of non-thermal plasma and subsequent antibiotic treatment for biofilm re-development prevention

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F20%3A43920800" target="_blank" >RIV/60461373:22330/20:43920800 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/20:10413521
Result on the web
<a href="http://file:///C:/Users/kasparkh/AppData/Local/Temp/FoliaCombinationofATBandplasma.pdf" target="_blank" >http://file:///C:/Users/kasparkh/AppData/Local/Temp/FoliaCombinationofATBandplasma.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12223-020-00796-3" target="_blank" >10.1007/s12223-020-00796-3</a>

Result language
angličtina
Original language name
Combination of non-thermal plasma and subsequent antibiotic treatment for biofilm re-development prevention
Original language description
The influence of non-thermal plasma (NTP) treatment on the prevention of antibiotic resistance of microbial biofilms was studied. Staphylococcus epidermidis and Escherichia coli bacteria and a yeast Candida albicans, grown on the surface of Ti-6Al-4V alloy used in the manufacture of prosthetic implants, were employed. Their biofilms were exposed to NTP produced by DC cometary discharge and subsequently treated with antibiotics commonly used for the treatment of infections caused by them: erythromycin (ERY), polymyxin B (PMB), or amphotericin B (AMB), respectively. All biofilms displayed significant reduction of their metabolic activity after NTP exposure, the most sensitive was S. epidermidis. The subsequent action of antibiotics caused significant decrease in the metabolic activity of S. epidermidis and E. coli, but not C. albicans, although the area covered by biofilm decreased in all cases. The combined effect of NTP with antibiotics was thus proved to be a promising strategy in bacterial pathogen treatment. © 2020, Institute of Microbiology, Academy of Sciences of the Czech Republic, v.v.i.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10606 - Microbiology

Project
<a href="/en/project/GA17-15936S" target="_blank" >GA17-15936S: Interaction of nanoparticles modified by natural compounds with biofilms of pathogenic microorganisms</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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