Comparison of lactic acid production by L. casei in batch, fed-batch and continuous cultivation, testing the use of feather hydrolysate as a complex nitrogen source

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F20%3A43920804" target="_blank" >RIV/60461373:22330/20:43920804 - isvavai.cz</a>
Result on the web
<a href="http://www.scielo.br/pdf/babt/v63/1516-8913-babt-63-e20190151.pdf" target="_blank" >http://www.scielo.br/pdf/babt/v63/1516-8913-babt-63-e20190151.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1590/1678-4324-2020190151" target="_blank" >10.1590/1678-4324-2020190151</a>

Result language
angličtina
Original language name
Comparison of lactic acid production by L. casei in batch, fed-batch and continuous cultivation, testing the use of feather hydrolysate as a complex nitrogen source
Original language description
A comprehensive comparison of the main fermentation parameters, productivity, yield and final Llactic acid concentration, obtained through batch, fed-batch and continuous cultivations using Lactobacillus casei CCDM 198 and a model cultivation medium was carried out. Using this data, a pulse-feed fed-batch process was established for testing chicken feather hydrolysate as a replacement for all complex nitrogen sources (yeast and beef extracts and peptone) in the medium. As comparably high values of productivity (about 4.0 g/L/h) and yield (about 98 %) were reached under all cultivation conditions, the maximum final Llactic acid concentration (116.5 g/L), as achieved through pulse-feed fed-batch fermentation, was chosen as the most important criterion for process selection. Fed-batch cultivation with chicken feather hydrolysate as both a complex nitrogen source and a neutralizing agent for maintaining constant culture pH yielded half the concentration of L-lactic acid compared to the model medium. We demonstrate here that chicken feather hydrolysate has potential for use in the production of L-lactic acid but its utilization requires further optimization. © 2020 by the authors.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Project
<a href="/en/project/LTACH17006" target="_blank" >LTACH17006: Production of biobutanol and succinic/lactic acid from lignocellulose biomass</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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