Ecstasy tablets: Rapid identification and determination of enantiomeric excess of MDMA

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F21%3A43922500" target="_blank" >RIV/60461373:22330/21:43922500 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22340/21:43922500 RIV/00007064:_____/21:N0000022 RIV/00023752:_____/21:43920769
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2468170921000771?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2468170921000771?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.forc.2021.100381" target="_blank" >10.1016/j.forc.2021.100381</a>

Result language
angličtina
Original language name
Ecstasy tablets: Rapid identification and determination of enantiomeric excess of MDMA
Original language description
The consumption of psychoactive substances is a worldwide problem and the sheer number of their seizures is alarming. These substances also include the synthetic drug 3,4-methylenedioxy-N-methylamphetamine (MDMA), also known as ecstasy, which is very often abused and widespread around the world. The number of ecstasy tablet seizures testifies to their popularity, especially on the dance music scene. One chiral center can be found in the MDMA molecule and therefore it may occur as two enantiomers, which are characterized by different physiological activity. Therefore, knowledge of the enantiomeric excess in the seized tablets is highly desirable. Within the work, dimensional and weight analysis were performed supported by photographic documentation. In addition, Raman and infrared (IR) spectroscopy were used to verify the content of the active substance in the tablets. Subsequently, the electronic circular dichroism (ECD) was used to construct a calibration curve for the determination of the enantiomeric excess of MDMA in the seized tablets. The obtained results show that most of the seized tablets contained MDMA as a racemate.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry

Project
<a href="/en/project/VJ01010043" target="_blank" >VJ01010043: Pharmacrime – forensic identification of prohormones and counterfeid medicine</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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