Investigation of Secondary Metabolites and Their Bioactive Potential in Various Iris Species and Cultivars Grown under Different Cultivation Conditions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F25%3A43932469" target="_blank" >RIV/60461373:22330/25:43932469 - isvavai.cz</a>
Result on the web
<a href="https://pubs.acs.org/doi/10.1021/acsomega.5c06354" target="_blank" >https://pubs.acs.org/doi/10.1021/acsomega.5c06354</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsomega.5c06354" target="_blank" >10.1021/acsomega.5c06354</a>
Alternative languages
Result language
angličtina
Original language name
Investigation of Secondary Metabolites and Their Bioactive Potential in Various Iris Species and Cultivars Grown under Different Cultivation Conditions
Original language description
This study analyzed the bioactive secondary metabolites in leaves and roots with rhizomes of various Iris species and cultivars (subgenus Iris and Limniris) grown under different conditions. Plants were cultivated in aeroponics and hydroponics and treated with a feather hydrolysate as an alternative nutrient source or arbuscular mycorrhizal fungi (AMF) to promote metabolite production. Phytochemical profiling was performed by using UHPLC-HRMS/MS, aided by in silico fragmentation for compound identification. Chemometric analyses revealed differences in the metabolic profiles between plant parts, including upregulation of phenolic acids, steroids, and C-glycosyl xanthones in the leaves and of stilbenes, triterpenoids, and benzophenones in the roots with rhizomes. Variations between the subgenera Iris and Limniris revealed possible chemotaxonomic markers, while cultivars of the same species showed a close similarity. Hydroponics resulted in upregulation of 232 metabolites, including flavone and isoflavonoid glycosides, compared to 42 upregulated metabolites in aeroponics, like xanthones and benzofurans. Neither feather hydrolysate nor AMF significantly altered the profile of detected metabolites. The correlation of the phytochemical profiles with biochemical assays of the Iris extracts indicated metabolites with cytotoxic, antimicrobial, and anti-inflammatory potential, including both known bioactive compounds (e.g., iridin, phalerin, or p-coumaric acid) and compounds with no published bioactivity data (e.g., irisjaponin A).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10400 - Chemical sciences
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Omega
ISSN
2470-1343
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
43
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
51256-51271
UT code for WoS article
001596590600001
EID of the result in the Scopus database
2-s2.0-105024133150