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Quality and safety assessment of hemp-based food products: Insights into seeds, flours, and oils

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F25%3A43933111" target="_blank" >RIV/60461373:22330/25:43933111 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0889157525011536?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0889157525011536?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jfca.2025.108337" target="_blank" >10.1016/j.jfca.2025.108337</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Quality and safety assessment of hemp-based food products: Insights into seeds, flours, and oils

  • Original language description

    The demand for hemp-derived food products, including oils, seeds, and flours, is growing because of their presumed nutritional benefits. However, concerns remain regarding the (unintentional) presence of psychotropic phytocannabinoids such as Δ⁹-tetrahydrocannabinol (Δ⁹-THC), even in products made from low-THC cultivars. This study presents a comprehensive analysis of 86 hemp food products purchased across the European market between 2022 and 2024. Using UHPLC-HRMS/MS, targeted analysis of 47 phytocannabinoids and 52 polyphenols was performed to assess both hazardous and health-promoting compounds. Phytocannabinoids, including trans-Δ⁹-THC, cis-Δ⁹-THC, and their precursor Δ⁹-THCA, were frequently quantified, especially in hemp seed oils. In several cases, calculated Δ⁹-THC intake exceeded the acute reference dose (ARfD) for a 70 kg adult after a standard serving, raising concerns about consumer safety, particularly for products labeled as &apos;THC-free&apos;. A shift toward lower Δ⁹-THC was observed in samples collected after the 2023 EU regulation setting maximum limits for this psychotropic compound. In addition to phytocannabinoids, polyphenols were quantified in all product types, with hemp seed flours showing the greatest diversity and highest concentrations of these bioactive secondary metabolites. In hemp oils, cannflavins A and B, unique lipophilic prenylflavonoids of Cannabis sativa L., were dominant. These findings highlight the value of advanced analytical approaches for characterization and quality control of hemp based foods. © 2025

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40500 - Other agricultural sciences

Result continuities

  • Project

    <a href="/en/project/GA22-20860S" target="_blank" >GA22-20860S: Anti-inflammatory properties of bioactive compounds isolated from Cannabis sativa L.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    JOURNAL OF FOOD COMPOSITION AND ANALYSIS

  • ISSN

    0889-1575

  • e-ISSN

  • Volume of the periodical

    148

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    12

  • Pages from-to

    nestránkováno

  • UT code for WoS article

    001583109200002

  • EID of the result in the Scopus database

    2-s2.0-105016663358