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ANALYSIS OF REACTION-TRANSPORT PHENOMENA IN A MICROFLUIDIC SYSTEM FOR DETECTION OF IGG

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F05%3A00014499" target="_blank" >RIV/60461373:22340/05:00014499 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    ANALYSIS OF REACTION-TRANSPORT PHENOMENA IN A MICROFLUIDIC SYSTEM FOR DETECTION OF IGG

  • Original language description

    The work is focused on mathematical modeling of reaction-transport processes in a microcapillary for immunoassay. A surface biochemical reaction between the immobilized antigen (Protein A) and antibody molecules (IgG) in a solution is studied. The modelis based on reaction-transport equations, the equation of electrostatics and the Navier-Stokes equations. Numerical solutions of the model equations and analytical solutions in special cases are determined. Parametrical studies are also carried out. We have looked for such sets of parameters when the time of the immunoassay between Protein A and IgG can be substantially shortened. The model can be used for design and development of ultra-fast diagnostic systems.

  • Czech name

    Analýza reakčně-transportních procesů v mikrofluidním systému pro detekci IgG

  • Czech description

    Práce je zaměřena na matematické modelování reakčně-transportních procesů v mikrokapiláře určené pro imunoanalýzu. Je studována povrchová interakce mezi imobilizovaným antigenem (Proteinem A) a protilátkami. Byla vykonána řada parametrických studií zaměřená na možné zkrácení doby imunoanalýzy. Model může být použit při výzkumu a vývoji rychlých diagnostických zařízení.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CI - Industrial chemistry and chemical engineering

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP104%2F03%2FD006" target="_blank" >GP104/03/D006: Study of microreactors for bioengineering application</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Proc. of 32th International Conference of Slovak Society of Chemical Engineering.

  • ISBN

    80-227-2224-3

  • ISSN

  • e-ISSN

  • Number of pages

    9

  • Pages from-to

  • Publisher name

    Slovak University of Technology

  • Place of publication

    Bratislava

  • Event location

    Tatranské Matliare, Slovensko

  • Event date

    May 23, 2005

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article