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Modelling and optimization of enzymatic separating microreactor

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F05%3A00014598" target="_blank" >RIV/60461373:22340/05:00014598 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Modelling and optimization of enzymatic separating microreactor

  • Original language description

    A mathematical model of an enzymatic separating microreactor with the electro-osmotic control of reaction component transport rates is analysed. The micro-reactor is considered in a form of a thin channel filled with a gel containing an immobilised enzyme and an adsorbent where the enzyme reaction, the molecular diffusion, the electro-osmotic flux and the adsorption take place. The substrate inhibited enzyme reaction splitting a non-ionic substrate to two non-ionic products is considered. The reactor operates in a periodic regime, when the channel entry is exposed to the periodic substrate concentration pulses. A chromatographic separation of reaction components, therefore, proceeds in the channel. Effects of principal operational parameters of the reactor system - the reaction channel length, the electric current density, the substrate inlet concentration, the rate of adsorption, and the enzyme activity - on resolution of the products at reactor outlet are analysed. The existence of o

  • Czech name

    Modelování a optimalizace enzymového separačního mikroreaktoru.

  • Czech description

    Je studován matematický model enzymového separačního mikroreaktoru využívajícího elektroosmotický transport reakčních složek. Reaktor je tvořen kanálkem vyplněným gelem s imobilizovaným enzymem a rozptýlenými mikročásticemi sorbentu. Substrát se enzymovou reakcí štěpí na dva produkty s různou silou sorpce. Reaktor je provozován v periodickém režimu a dochází ke střídání reakční a separační periody. Je vykonána optimalizace geometrických a provozních parametrů systému v závislosti na základních provozních parametrech.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CI - Industrial chemistry and chemical engineering

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA104%2F01%2F1319" target="_blank" >GA104/01/1319: Multifunctional chemical and biochemical reactors - modeling and experiments</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Bioprocess and Biosystems Engineering

  • ISSN

    1615-7591

  • e-ISSN

  • Volume of the periodical

    28

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    8

  • Pages from-to

    123-130

  • UT code for WoS article

  • EID of the result in the Scopus database