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Conformational and Thermal Stability Studies of Sequential Oligopeptides (Lys-Ala-Ala)n in Aqueous Solution

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F08%3A00022855" target="_blank" >RIV/60461373:22340/08:00022855 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Conformational and Thermal Stability Studies of Sequential Oligopeptides (Lys-Ala-Ala)n in Aqueous Solution

  • Original language description

    Sequential cationic oligopeptides of the different length of peptide chain, H-(L-lysyl-L-alanyl-L-alanine)n-OMe, (KAA)n, n = 1, 2 and 3, were synthesized and their solution conformations were investigated over a range of temperatures using a combinationof spectroscopic techniques with emphasis to vibrational (VCD) and electronic (ECD) circular dichroism spectroscopies. Singular value decomposition (SVD) method of factor analysis (FA) was applied to help understand the thermal stability and thermally induced conformational changes.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP203%2F06%2FP371" target="_blank" >GP203/06/P371: Study the conformational changes of polycationic sequential polypeptide complexes with porphyrins using vibrational circular dichroism spectroscopy</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Peptides 2008 - Chemistry of Peptides in Life Science, Technology and Medicine

  • ISBN

    978-952-92-5198-8

  • ISSN

  • e-ISSN

  • Number of pages

    2

  • Pages from-to

  • Publisher name

    The Finnish Peptide Society

  • Place of publication

    Finsko

  • Event location

    Helsinki, Finsko

  • Event date

    Aug 31, 2008

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article